Osaka (大阪 Ōsaka) is a city in the Kansai region of Japan’s main island of Honshu, a designated city under the Local Autonomy Law, the capital city of Osaka Prefecture and also the largest part of the Keihanshin metropolis, which comprises three major cities of Japan: Kyoto, Osaka and Kobe. Located at the mouth of the Yodo River on Osaka Bay, Osaka is Japan’s third largest city by population after Tokyo (special wards) and Yokohama, as well as an economic hub.